Experimental heart transplantation
نویسندگان
چکیده
منابع مشابه
Pre-Transplant Therapy in Experimental Heart Transplantation
Heart transplantation is a life-saving procedure for patients with end-stage cardiac dysfunction. Currently one-year graft survival ranges between 77-88%, three-year survival between 77-79% and five-year survival between 67-73% (http://www.americanheart.org/presenter.jhtml?identifier=4588). Despite these encouraging results, primary graft failure accounts for about 23% of deaths in the first 90...
متن کاملRibonuclease (RNase) Prolongs Survival of Grafts in Experimental Heart Transplantation
BACKGROUND Cell damage, tissue and vascular injury are associated with the exposure and release of intracellular components such as RNA, which promote inflammatory reactions and thrombosis. Based on the counteracting anti-inflammatory and cardioprotective functions of ribonuclease A (RNase A) in this context, its role in an experimental model of heart transplantation in rats was studied. METH...
متن کاملAge-dependent chronic rejection after experimental heart transplantation.
BACKGROUND The progressive decline of allograft function is predominantly a consequence of chronic rejection, but the etiology of this process is not fully understood. To evaluate the influence of age we performed heart transplantation in an experimental model of chronic rejection using inbred rats of different age. METHODS Lewis rats served as donors and F344 rats were used as recipients. Yo...
متن کاملHeart transplantation.
Although the number of available donor hearts severely limits the epidemiologic impact of heart transplantation on patients with heart failure, patients with end-stage heart failure unresponsive to medical management currently have no other viable alternatives. Destination therapy with a ventricular assist device is the closest toward approaching clinical reality but has been plagued with probl...
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BACKGROUND Uterus transplantation (UTx) is developed in animal models as a future method to treat uterine factor infertility. METHODS All published studies in the area of UTx research were identified. Aspects relating to surgery, cold-ischemia/reperfusion, rejection, immunosuppression, pregnancy, ethics and institutional requirements were examined. RESULTS Uterus retrieval surgery has been ...
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ژورنال
عنوان ژورنال: The Journal of Thoracic and Cardiovascular Surgery
سال: 1983
ISSN: 0022-5223
DOI: 10.1016/s0022-5223(19)39194-9